Search on: VIRUSES, ONCOLYTIC 
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Descriptor English:   Oncolytic Viruses 
Descriptor Spanish:   virus oncolíticos 
Descriptor Portuguese:   Vírus Oncolíticos 
Synonyms English:   Oncolytic Virus
Virus, Oncolytic
Viruses, Oncolytic  
Tree Number:   B04.700
Definition English:   Tumor-selective, replication competent VIRUSES that have antineoplastic effects. This is achieved by producing cytotoxicity-enhancing proteins and/or eliciting an antitumor immune response. They are genetically engineered so that they can replicate in CANCER cells but not in normal cells, and are used in ONCOLYTIC VIROTHERAPY. 
Indexing Annotation English:   ONCOGENIC VIRUSES is available
See Related English:   Oncolytic Virotherapy
 
History Note English:   2006, 1966-1993; use VIRUSES 1994-2005 
Allowable Qualifiers English:  
CH chemistry CL classification
DE drug effects EN enzymology
GE genetics GD growth & development
IM immunology IP isolation & purification
ME metabolism PY pathogenicity
PH physiology RE radiation effects
UL ultrastructure  
Record Number:   50452 
Unique Identifier:   D050504 

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